The Palix Foundation is a private philanthropic organization dedicated to improving the health and well-being of individuals, families, and communities across Alberta and beyond. The Foundation's flagship initiative, the Alberta Family Wellness Initiative (AFWI) aligns science, policy, and practice in the area of brain development to support the foundations of all health. The AFWI partnered with the National Scientific Council on the Developing Child at Harvard University and the FrameWorks Institute to develop the Brain Story and Resilience Scale, which translates this complex science into an accessible, engaging story-form. The AFWI has mobilized transformative system shifts driven by the application of science at the individual, organization, and community levels across the health, education, child services, and justice sectors.